One species of chanca piedra – Phyllanthus niruri –is safe and non-toxic. Common side effects are mild and include [ 32, 25, 23, 158]: Chanca piedra is also used in cosmetic, dental, and skincare products, including hair dye, face creams, and toothpaste [ 11]. Bioactive Components Additionally, chanca piedra may reduce blood sugar levels. Its combination with anti-diabetes therapies (e.g. glimepiride, insulin, rosiglitazone, tolbutamide) might cause excessive drops in blood sugar levels [ 57, 73, 74]. Kidney stones are deposits of minerals and salts that build up in the kidneys or urinary tract. In clinical studies with over 200 people with kidney stones, chanca piedra ( Phyllanthus niruri) reduced their kidney stones, helping to clear the minerals and salt deposits [ 21, 22, 23, 24, 25, 26].

Ranilla LG et al. Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin America. Bioresour Technol. 2010 Jun;101(12):4676-89. It grows 50–70cm (20–28in) tall and bears ascending herbaceous branches. The bark is smooth and light green. It bears numerous pale green flowers which are often flushed with red. The fruits are tiny, smooth capsules containing seeds.Jayaram, S. and Thyagarajan, S. P. Inhibition of HBsAg secretion from Alexander cell line by Phyllanthus amarus. Indian J Pathol.Microbiol. 1996;39(3):211-215. View abstract. Este artigo sobre a ordem Malpighiales, integrado no Projeto Plantas é um esboço. Você pode ajudar a Wikipédia expandindo-o. Es hat mich überrascht, wie schnell eine spürbare Besserung nach dem Trinken des Tees eintrat. Mich plagte ein Nierenstein. Nach einer 1-wöchigen Trinkkur verspürte ich kein Schmerz mehr und eine Ultraschalluntersuchung meiner Niere ergab keinen krankhaften Befund. Mahat MA, Patil BM. Evaluation of antiinflammatory activity of methanol extract of Phyllanthus amarus in experimental animal models. Indian Journal of Pharmaceutical Sciences 2007;33-36.

According to some claims, chanca piedra may have several beneficial effects on different body systems. However, there’s little research to support these claims. Kidney stones Musuamba CT, Cimanga RK Dooghe L et al. In vitro antiplasmodial and cytotoxic activities of ethanol extracts of apical stem of Phyllanthus amarus Schum. et Thonn. (Euphorbiaceae). Journal of Complementary and Integrative Medicine 2010;7(1)Kumar NG, Nair AN Raghunandanan VR et al. Hypoglycaemic effect of Phyllanthus niruri leaves in rabbits. Kerala Journal of Veterinary Science 1989;20(1):77-80. In one study of 56 people with kidney stones who took 1 cup of hot water infused with an herbal sachet containing 4.5 grams of chanca piedra twice daily, researchers found that the kidney stones decreased in size and number in about two-thirds of participants ( 3).

Chatterjee, M., Sarkar, K., and Sil, P. C. Herbal (Phyllanthus niruri) protein isolate protects liver from nimesulide induced oxidative stress. Pathophysiology. 2006;13(2):95-102. View abstract. Bharathi KN, Dattani V. Evaluation of type-I anti-diabetic activity of Phyllanthus niruri and combination of Phyllanthus niruri and Gymnema sylvestre. Asian Journal of Experimental Sciences 2010; Naik, A. D. and Juvekar, A. R. Effects of alkaloidal extract of Phyllanthus niruri on HIV replication. Indian J Med Sci 2003;57(9):387-393. View abstract. Já a espécie Phyllanthus amarus apresenta substâncias anti-cancerígenas e anti-inflamatórias [1 ], além de combater o vírus da hepatite B [3 ], o fato que levou uma empresa norte-americana a patentear a planta para usá-la num medicamento contra esta doença. [1 ] [2 ] Dieselbe „steinbrechende“ Qualität hilft auch bei Gallensteinen. In der Tat hat der Steinbrecher Tee die Fähigkeit, Cholesterin zu senken, eine wichtige Ursache für Gallensteine. Chanca Piedra ist schmerzlinderndLondhe, J. S., Devasagayam, T. P., Foo, L. Y., and Ghaskadbi, S. S. Radioprotective properties of polyphenols from Phyllanthus amarus Linn. J Radiat.Res 2009;50(4):303-309. View abstract. Rao, M. V. and Alice, K. M. Contraceptive effects of Phyllanthus amarus in female mice. Phytother.Res 2001;15(3):265-267. View abstract. It’s one of the lesser-known South American herbs, and has several different names depending on where you are in the World, including Shatterstone, Chanca Piedra (which means ‘stone breaker’ in Peru) and Bhumyamalaki.

Lee NYS et al. The pharmacological potential of Phyllanthus Niruri. J Pharm Pharmacol. 2016 Aug;68(8):953-69. Chezhiyan N, Saraswathy S Vasumathi R. Studies on organic manures, biofertilizers and plant density on growth, yield and alkaloid content of bhumyamalaki (Phyllanthus amarus Schum. and Thonn.). South Indian Horticulture 2003;51:96-101. Okoli CO et al. Studies on the possible mechanisms of antidiabetic activity of extract of aerial parts of Phyllanthus niruri. Pharm Biol. 2011 Mar;49(3):248-55. Since chanca piedra may reduce blood pressure, it may also increase the effects of blood pressure-lowering drugs [ 57, 58, 59]. Alguns estudos preliminares demonstraram que o extrato da quebra pedra ajuda a proteger o fígado contra os danos causados pelo álcool.Kumar MS, Jaiprakash B Hukkeri VI. Preventive effect of Phyllanthus amarus on prostatic hyperplasia. Hamdard Medicus 2006;114-117. Brook, M. G. Effect of Phyllanthus amarus on chronic carriers of hepatitis B virus. Lancet 10-29-1988;2(8618):1017-1018. View abstract. McPartland JM. Viral hepatitis treated with Phyllanthus amarus and milk thistle (Silybum marianum): a case report [corrected]. Complementary Medicine International 1996;3(2):40-42.